PD 146176 l Mesylate 2011 Jan 1

2011 Jan 1

Entinostat (MS-275) was orally dosed to mice at 49 mg/kg once daily 5 days per week for 4 weeks in the xenograft tumor model

is a potent PKCε activator for use in the treatment of neurodegenerative diseases

Eisenberg MJ

Szyndralewiez C

PD 146176 l Mesylate 2011 Jan 1PD 146176 is a specific, non competitve 15 lipoxygenase (15 LOX) inhibitor with Ki of 197 nM. Product information CAS Number: 4079 26 9 Molecular Weight: 237. 32 Formula: C15H11NS Synonym: NSC168807 Chemical Name: 6,11 dihydro [1]benzothiopyrano[4,3 b]indole Smiles: C1SC2=CC=CC=C2C2NC3=CC=CC=C3C=21 InChiKey: ZGOOPZVQMLHPFM UHFFFAOYSA N InChi: InChI=1S C15H11NS c1 3 7 13 10(5 1)12 9 17 14 8 4 2 6 11(14)15(12)16 13 h1 8,16H,9H2 Technical Data