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These two pathways have overlapping functions, but insulin is mainly involved in the regulation of metabolism, and the Growth Hormone/IGF-1 pathway plays an important role in the processes of growth, development and possibly life expectancy

Published literature includes over 100 studies examining its effects in various in-vitro and animal model systems, with research groups investigating gastrointestinal cytoprotection, tendon and ligament tissue models, and neurological signaling pathways

M.Han Yoon ParkJ.HanJ.-S.et al (2018)

In laboratory settings, Ipamorelin functions as a selective agonist of the growth hormone secretagogue receptor (GHS-R1a), also known as the ghrelin receptor

The search plan was made in Medline for Pubmed with the following mesh terms: IGF-1 and metabolism, carbohydrate, lipids, proteins, amino acids, metabolic syndrome, cardiovascular disease, diabetes between the years 19632015

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