SB-334867 (base) - an orexin antagonist. CAS# 792173-99-0 size:2mg solid 2016 Feb 12

2016 Feb 12

which is the first selective and potent inhibitor of the H3K27 histone demethylases UTX and JMJD3

Chemical Name: 2-(4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl)-1-(1H-1

Guillausseau PJ

1-8 µM) inhibits the growth of HUVECs in a dose-dependent manner

SB-334867 (base) - an orexin antagonist. CAS# 792173-99-0 size:2mg solid 2016 Feb 12SB 334867, an orexin antagonist, CAS No. 792173 99 0, is an orexin antagonist. SB 334867 was the first non peptide antagonist developed that is selective for the orexin receptor subtype OX1, with around 50x selectivity for OX1 over OX2 receptors. It has been shown to produce sedative and anorectic effects in animals, and has been useful in characterising the orexinergic regulation of brain systems involved with appetite and sleep, as well as other