Telotristat Catalog No.:M9043-10 Chemical Name: 8-(dimethylamino)-3-(2-{[(5-methyl-1

Chemical Name: 8-(dimethylamino)-3-(2-{[(5-methyl-1

Molecular Weight: 658

It can cause a dramatic reduction of the intracellular Notch level and lead to significantly decreased expression of the Notch transcriptional target genes

and the human MDA-MB-468 cell xenograft model

It exhibits a wide variety of biological activities

Telotristat Catalog No.:M9043-10 Chemical Name: 8-(dimethylamino)-3-(2-{[(5-methyl-1Telotristat, also known as LP 778902, is the acid form of Telotristat ethyl, and the active metabolite of LX1606 (Telotristat etiprate), which is an orally bioavailable, small molecule, tryptophan hydroxylase (TPH) inhibitor and serotonin synthesis inhibitor with potential antiserotonergic activity. Blocking peripheral serotonin synthesis by telotristat reduces severity of both chemical and infection induced intestinal inflammation. Product