OG-L002 - LSD1 Inhibitor. CAS# 1357302-64-7 size:10mg solid 6 mg/mL in DMSO

6 mg/mL in DMSO

Molecular and cellular pharmacology of the hypoxia-activated prodrug TH-302

Hhat inhibitor could offer a new treatment modality for cancers characterized by Shh overexpression and extremely poor prognoses

Nature Chem Biol

This concentration is about 100

OG-L002 - LSD1 Inhibitor. CAS# 1357302-64-7 size:10mg solid 6 mg/mL in DMSOOG L002, CAS No. 1357302 64 7, is a highly potent and specific inhibitor of Lysine Specific Demethylase 1 (LSD1). It inhibits LSD1 in biochemical assay with an IC50 ~20 nM, and has moderate inhibitory activity against monoamine oxidases MAO A and MAO B with IC50 ~1. 38 M and 0. 72M respectively. It potently repressed herpes simplex virus (HSV) IE gene expression, genome replication, and reactivation from latency. OG L002 suppressed primary lytic