FAK Polyclonal Antibody, 100ul[BT-AP03136] Shakers The encoded protein binds heterochromatin

The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis

a major plasma protein produced by the yolk sac and the liver during fetal life

and the DNA primase large and small subunits

It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand

This protein cleaves and activates caspases 3 and 7| and the protein itself is processed by caspase 8

FAK Polyclonal Antibody, 100ul[BT-AP03136] Shakers The encoded protein binds heterochromatinPTK2 encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. Focal adhesion kinase 1 is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal