LX-1031 - CAS# 945976-76-1 Catalog No.:M10754-2 which can be significantly enhanced

which can be significantly enhanced when combined with radiation

CAS Number: 1260533-36-5

InChi: InChI=1S/C24H18N4O/c1-27-17-9-4-2-7-14(17)20-21-16(13-26-24(21)29)19-15-8-3-5-10-18(15)28(12-6-11-25)23(19)22(20)27/h2-5

Chemical Name: 2-[[(2-Hydroxy-1-naphthalenyl)methylene]amino]- N -(1-phenylethyl)benzamide

Molecular Weight: 194

LX-1031 - CAS# 945976-76-1 Catalog No.:M10754-2 which can be significantly enhancedLX 1031 is a THP inhibitor (a tryptophan 5 hydroxylase inhibitor) that reduces 5 HT levels for the potential treatment of irritable bowel syndrome. LX 1031 has potential for illnesses characterized by excess 5 HT, such as diarrhea predominant irritable bowel syndrome (IBS D) and carcinoid diarrhea. In vitro, inhibition of TPH1 occurred in 10( 8) 10( 7) mol L( 1) range. In vivo in rodents, LX 1031 has no effect on brain 5 HT while dose dependently