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CP-724714 - CAS# 383432-38-0 Size:Solid 2 mg OC(CN1C=NC=C1)(P(O)(O)=O)P(O)(O)=O

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CP-724714 - CAS# 383432-38-0 Size:Solid 2 mg OC(CN1C=NC=C1)(P(O)(O)=O)P(O)(O)=OCP 724714 is An orally bioavailable quinazoline with potential antineoplastic activity. CP 724,714 selectively binds to the intracellular domain of HER2, reversibly inhibiting its tyrosine kinase activity and resulting in suppression of tumor cell growth. HER2, a member of the epidermal growth factor receptor (EGFR) family, is overexpressed in many adenocarcinomas, particularly breast cancers. Product information CAS Number: 383432 38 0 Molecular

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Description

OC(CN1C=NC=C1)(P(O)(O)=O)P(O)(O)=O

ClH/c1-21(2)12-5-13-22-18-7-4-3-6-15(18)8-9-16-10-11-17(20)14-19(16)22

Birth Defects Res B Dev Reprod Toxic

Chemical Name: N'1-{2-fluoro-4-[(2-{[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]amino}pyridin-4-yl)oxy]phenyl}-N1-(4-fluorophenyl)cyclopropane-1

AC-55541 may be useful in probing the physiological functions of PAR2 receptors

CP-724714 - CAS# 383432-38-0 Size:Solid 2 mg OC(CN1C=NC=C1)(P(O)(O)=O)P(O)(O)=OCP 724714 is An orally bioavailable quinazoline with potential antineoplastic activity. CP 724,714 selectively binds to the intracellular domain of HER2, reversibly inhibiting its tyrosine kinase activity and resulting in suppression of tumor cell growth. HER2, a member of the epidermal growth factor receptor (EGFR) family, is overexpressed in many adenocarcinomas, particularly breast cancers. Product information CAS Number: 383432 38 0 Molecular

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