pardoprunox - CAS# 269718-84-5 nd Library of Histone Demethylase 6(8):e23667
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pardoprunox - CAS# 269718-84-5 nd Library of Histone Demethylase 6(8):e23667pardoprunox, CAS No. 269718 84 5, also known as SLV 308; DU 126891; SME 308, is dopamine D2 5 HT1A receptor agonist potentially for the treatment of Parkinson's disease. It was also being investigated for the treatment of depression and anxiety but these indications appear to have been abandoned. Pardoprunox acts as a D2 (pKi = 8. 1) and D3 receptor (pKi = 8. 6) partial agonist (IA = 50% and 67%, respectively) and 5 HT1A receptor (pKi = 8. 5) full
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