SB225002 Catalog No.:M8483-2 PMID: 15454212

PMID: 15454212

It serves as a useful chemical tool to further validate and develop novel treatments of osteoporosis via promoting bone formation

4% Tween-80

Chemical Name: N-[(4-fluorophenyl)methyl]-5-hydroxy-1-methyl-2-{2-[(5-methyl-1

CAS Number: 2139348-63-1

SB225002 Catalog No.:M8483-2 PMID: 15454212SB225002 is a novel and potent microtubule inhibitor and CXCR2 antagonist with potential anticancer activity. SB225002 promotes mitotic catastrophe in chemo sensitive and resistant ovarian cancer cells independent of p53 status in vitro. SB225002 induces apoptosis in both wild type and p53 deficient ovarian cancer (OVCA) cells through alternative mechanisms. SB225002 promotes mitotic catastrophe, as evidenced by the accumulation of mitotic cells with