Bosentan 7 Tosylate 4-dimethoxyphenyl)-N-(2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)carbamate

4-dimethoxyphenyl)-N-(2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)carbamate

is the active flavor constituent of the seeds of Guinea pepper (Aframomum melegueta or grains of paradise)

leading to a significant decline in testosterone production

1-3H3/b10-4+

Nafamostat mesilate inhibits gemcitabine-induced NF-kappaB activation

Bosentan 7 Tosylate 4-dimethoxyphenyl)-N-(2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)carbamateBosentan is a mixed Endothelin Receptor Antagonist which is used as a vasodilator. Bosentan is an inhibitor of ETAR and ETBR. It is used for the treatment of pulmonary artery hypertension (PAH). Bosentan blocks the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and lead to high blood pressure. Product information CAS Number: 147536 97 8 Molecular Weight: 551. 61 Formula: C27H29N5O6S Chemical Name: 4 tert