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PF-562271 besylate - CAS# 939791-38-5 Catalog No.:M10567-2 PubMed PMID: 23991670

PF-562271 besylate - CAS# 939791-38-5 Catalog No.:M10567-2 PubMed PMID: 23991670

Name: PF-562271 besylate - CAS# 939791-38-5 Catalog No.:M10567-2 PubMed PMID: 23991670
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PF-562271 besylate - CAS# 939791-38-5 Catalog No.:M10567-2 PubMed PMID: 23991670PF 562271 Besylate, also known as PF 562,271 and PF 271, is an orally bioavailable small molecule and ATP competitive focal adhesion kinase (FAK) inhibitor with potential antineoplastic and antiangiogenic activities. PF 562271 inhibits the tyrosine kinase FAK, and to a lesser extent, proline rich tyrosine kinase (PYK2), which may inhibit tumor cell migration, proliferation, and survival. Note: PF 562271 benzesulfonate is also called PF 562271

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Description

PubMed PMID: 23991670

is a novel first in class

InChi: InChI=1S/C21H28N8O3S2/c1-14-16(13-27-3-5-29(6-4-27)34(2

It inhibits epithelial-to-mesenchymal transition

decreasing immobility time in the forced swim test

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