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Kenpaullone - CAS# 142273-20-9 60171 Epub 2019 Jan 17

Kenpaullone - CAS# 142273-20-9 60171 Epub 2019 Jan 17

Name: Kenpaullone - CAS# 142273-20-9 60171 Epub 2019 Jan 17
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SKU: 75959554178
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Kenpaullone - CAS# 142273-20-9 60171 Epub 2019 Jan 17Kenpaullone, CAS No. 142273 20 9, is a potent inhibitor of CDK1 cyclin B (IC50 = 400 nM), CDK2 cyclin A (IC50 = 680 nM), CDK2 cyclin E (IC50 = 7. 5 uM) and CDK5 p25 (IC50 = 850 nM). Kenpaullone inhibits CDK2 cyclin A, CDK2 cyclin E and CDK5 cyclin p35 (IC50 values are 0. 68, 7. 5 and 0. 85 M respectively). Product information CAS Number: 142273 20 9 Molecular Weight: 327. 18 Formula: C16H11BrN2O Synonym: NSC664704 NSC 664704 Kenpaullone NSC 664704

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Description

Epub 2019 Jan 17

ALK3 and ALK6

is a nucleophosmin inhibitor

8 μM across a selected panel of cancer cell lines

F 11440 was 4- to 20-fold more potent than flesinoxan

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