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ML324 - JMJD2 Histone Demethylase Inhibitor. CAS# 1222800-79-4 size:10mg solid 1152/ajpcell

SKU: 76514984526

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ML324 - JMJD2 Histone Demethylase Inhibitor. CAS# 1222800-79-4 size:10mg solid 1152/ajpcellML324, CAS No. 1222800 79 4, is a potent, selective and cell permeable inhibitor of Jumonji domain containing protein 2 (JMJD2) histone demethylase with IC50 ~0. 92 M toward JMJD2E. It has excellent in vitro ADME properties, and it could effectively block both herpes simplex virus (HSV) and human cytomegalovirus (hCMV) infection via inhibition viral IE gene expression. ML324 suppresses the formation of HSV plaques, even at high MOI, and blocks HSV 1

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Description

1152/ajpcell

Alrefai WA

587871-26-9

In cellular assays CP-690550 showed potent effects in the IL-2 blast proliferation assay (IC50 ~11 nM

Ishizaki T

ML324 - JMJD2 Histone Demethylase Inhibitor. CAS# 1222800-79-4 size:10mg solid 1152/ajpcellML324, CAS No. 1222800 79 4, is a potent, selective and cell permeable inhibitor of Jumonji domain containing protein 2 (JMJD2) histone demethylase with IC50 ~0. 92 M toward JMJD2E. It has excellent in vitro ADME properties, and it could effectively block both herpes simplex virus (HSV) and human cytomegalovirus (hCMV) infection via inhibition viral IE gene expression. ML324 suppresses the formation of HSV plaques, even at high MOI, and blocks HSV 1

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