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SNIPER(ER)-87 Catalog No.:M7563-10 Epub 2013 Feb 7

SNIPER(ER)-87 Catalog No.:M7563-10 Epub 2013 Feb 7

Name: SNIPER(ER)-87 Catalog No.:M7563-10 Epub 2013 Feb 7
Brand: psychwardcomics.com
SKU: 83039336999
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SNIPER(ER)-87 Catalog No.:M7563-10 Epub 2013 Feb 7SNIPER(ER) 87 is a potent and selective estrogen receptor (ER) Degrader (Specific and Nongenetic IAP dependent Protein Erasers or SNIPER) (DC50 = 3 nM). SNIPER(ER) 87 comprises the IAP binding ligand LCL 161 (Cat. No. 7178) joined by a linker to the estrogen binding moiety 4 hydroxytamoxifen (Cat. No. 3412). The product decreases ER levels in breast cancer cells in vitro and in mouse ovaries in vivo. SNIPER(ER) 87 also reduces ER levels and inhibits

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Epub 2013 Feb 7

Smiles: OC(=O)CCCOC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O

460(2):333-40

2(9):938-42

Yoshimura A

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