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DSIP is particularly relevant for people who experience any of the following patterns: Early morning waking (24am) that has persisted despite addressing sleep hygiene Unrested sleep feeling unrefreshed regardless of hours slept High nighttime cortisol the wired at night pattern associated with HPA axis dysregulation Recovery-limited athletic performance plateaus in training despite adequate volume and nutrition High cognitive demand executives, creatives, and knowledge workers whose cognitive performance degrades noticeably with poor sleep Post-illness or post-surgery recovery where deep sleep is essential for accelerated healing It is also frequently used alongside other sleep-supportive peptides and interventions as part of a comprehensive recovery protocol

Dead cells were stained with SYTOX blue or 7-AAD (BioLegend)

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It is available through specialist NHS weight management services, though access may vary by Integrated Care Board (ICB)

However, researchers had been unable to identify the precise mechanisms at play