TPT-260 dihydrochloride - CAS# 2076-91-7 526 SE AZ3451 attenuates chondrocytes apoptosis by

AZ3451 attenuates chondrocytes apoptosis by activating autophagy in vitro

The efficacy of Ethamsylate to reduce intraventricular hemorrhage is associated with a reduction of thromboxane A2 and prostacyclin biosynthesis

116(7):937-943

is an orally bioavailable inhibitor of the c-Met receptor tyrosine kinase with potential antineoplastic activity

194(3):1122-30

TPT-260 dihydrochloride - CAS# 2076-91-7 526 SE AZ3451 attenuates chondrocytes apoptosis byTPT 260 2HCl, also known as R55, is a thiophene thiourea derivative with molecule weight 260. 00 in free base form. There is no formal name yet, we temporally call this molecule as TPT 260. TPT260 acts as a chaperone to stabilize the retromer complex against thermal denaturation (Kd = ~ 5 M). In cultured hippocampal neurons, TPT 260 dose dependently increases the level of retromer proteins, redirects APP from the endosome, and reduces the formation of