Ponatinib - CAS# 943319-70-8 size:2mg solid Epub 2009 Aug 4
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Ponatinib - CAS# 943319-70-8 size:2mg solid Epub 2009 Aug 4Ponatinib, CAS No. 943319 70 8, is an orally bioavailable multitargeted receptor tyrosine kinase (RTK) inhibitor with potential antiangiogenic and antineoplastic activities. Multitargeted tyrosine kinase inhibitor AP24534 inhibits unmutated and all mutated forms of Bcr Abl, including T315I, the highly drug therapy resistant missense mutation of Bcr Abl. This agent also inhibits other tyrosine kinases including those associated with vascular
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