PF-2545920 - CAS# 898562-94-2 Catalog No.:M6450-10 PubMed PMID: 28711582

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PF-2545920 - CAS# 898562-94-2 Catalog No.:M6450-10 PubMed PMID: 28711582PF 2545920, also known as Mardepodect, CAS No. 898562 94 2, is a phosphodiesterase inhibitor selective for the PDE10A subtype, which is potentially useful for the treatment of schizophrenia. Phosphodiesterase 10A (PDE10A) is highly expressed in striatal medium spiny neurons of both the direct and indirect output pathways. PDE10A inhibitors have shown behavioral effects in rodent models that predict antipsychotic efficacy. PF 2545920 is active in a

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