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This controlled elimination of compromised cells aids their clearance and fosters subsequent mucosal repair and regeneration (167)

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When accompanied by metabolic disorders, such as IR and dyslipidaemia, it can lead to hyperlipidaemia, hypertension, metabolic syndrome and diabetes

Such bidirectional interaction between hyperandrogenism and insulin resistance/hyperinsulinemia likely plays a key role in the pathogenesis of PCOS 12,13,14 , since elevated testosterone promotes obesity and insulin resistance/hyperinsulinemia by altering body composition and insulin signaling in skeletal muscle and adipose tissue, while hyperinsulinemia contributes to increase androgen levels via ovarian-dependent mechanisms 5

a great deal or quite a bit (27% vs

Effectiveness of a weight loss intervention in postpartum women: results from a randomized controlled trial in primary health care