L-165041 Size:Solid 10 mg 11(2)28)8-14-18(16)25(33)20-19(24(14)32)22(30)12-5-3-4-6-13(12)23(20)31
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L-165041 Size:Solid 10 mg 11(2)28)8-14-18(16)25(33)20-19(24(14)32)22(30)12-5-3-4-6-13(12)23(20)31L 165041, also known as L 165,041, is a potent and selective agonist of the nuclear receptor PPAR (Ki = 9 nM, EC50 = ~500 nM for hPPAR ). L 165041 promotes VEGF mRNA stabilization in HPV18 harboring HeLa cells through a receptor independent mechanism. L 165041 inhibits VEGF induced angiogenesis, but the antiangiogenic effect is not related to PPAR. L 165041 inhibits rat vascular smooth muscle cell proliferation and migration via inhibition of cell
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