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KS-176 - CAS# 1253452-78-6 one Methyltransferase Evaluation of PAI-039 [{1-benzyl-5-[4-(trifluoromethoxy)phenyl]-1H-indol-3-yl}(oxo)acetic acid]

KS-176 - CAS# 1253452-78-6 one Methyltransferase Evaluation of PAI-039 [{1-benzyl-5-[4-(trifluoromethoxy)phenyl]-1H-indol-3-yl}(oxo)acetic acid]

Name: KS-176 - CAS# 1253452-78-6 one Methyltransferase Evaluation of PAI-039 [{1-benzyl-5-[4-(trifluoromethoxy)phenyl]-1H-indol-3-yl}(oxo)acetic acid]
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KS-176 - CAS# 1253452-78-6 one Methyltransferase Evaluation of PAI-039 [{1-benzyl-5-[4-(trifluoromethoxy)phenyl]-1H-indol-3-yl}(oxo)acetic acid]KS 176, CAS No. 1253452 78 6, is a potent specific inhibitor of Breast Cancer Resistance Protein (BCRP) ATP binding cassette sub family G member 2 (ABCG2). Product information CAS Number: 1253452 78 6 Molecular Weight: 405. 40 Formula: C22H19N3O5 Synonym: KS 176 KS176 KS 176 Chemical Name: N [4 (2 Hydroxyethyl)phenyl] 2 [(4 nitrobenzoyl)amino]benzamide Smiles: [O ][N+](=O)C1C=CC(=CC=1)C(=O)NC1=CC=CC=C1C(=O)NC1C=CC(CCO)=CC=1 InChiKey: LTWQQWSXYYXVGA

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Description

Evaluation of PAI-039 [{1-benzyl-5-[4-(trifluoromethoxy)phenyl]-1H-indol-3-yl}(oxo)acetic acid]

Smiles: CN1C=C(C=N1)C1C=CC(=CC=1)S(=O)(=O)N1C=C(/C=C/C(=O)NC2=CC=CC=C2N)C=C1

and PC-3 cells

is a highly potent and selective irreversible EGFR inhibitor

AZD-2281 is applied to SW620 cell lysates

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