Ixabepilone 0160 which is a DNA minor

which is a DNA minor groove binder used fluorochrome for visualizing cellular DNA

Miltefosine targets cellular membranes

InChiKey: HRLQRNBAJCQMMG-UHFFFAOYSA-N

It has minimal activity (IC50 >1 µM) against HDAC4

Formula: C29H35N7O4

Ixabepilone 0160 which is a DNA minorIxabepilone (also known as azaepothilone B, or BMS 247550) is an orally bioavailable microtubule inhibitor. Ixabepilone was a semisynthetic analogue of epothilone B with antineoplastic activity. Ixabepilone binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arresting cells in the G2 M phase of the cell cycle and inducing tumor cell apoptosis. This agent demonstrates antineoplastic activity against taxane