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doi: 10.1155/2022/7769355 259 WangLAnHYuFYangJDingHBaoYet al

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Notably, MCP-1, also known as chemokine ligand 2 (CCL2), plays a pivotal role in promoting BBB instability by facilitating the recruitment of monocytes/Ms into CNS compartment and contributing to the reorganization of TJ and the actin cytoskeleton (Stamatovic et al., 2003)

Cell pellets were thawed, resuspended in 300 l cold lysis buffer (PBS and 1 mM EDTA), homogenized and centrifuged (12,000 g

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Body Temperature Regulation: 4