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Notably, patients with variants in the linker, MTS, or P domains exhibited later onset, milder epilepsy severity, and better responsiveness to antiepileptic drugs, suggesting that the functional domain distribution of LONP1 variants may influence the severity grading of epileptic phenotypes [89]

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This regular sleep disturbance can have a major impact on your quality of life and you may experience: Mood disturbances Insomnia Increased fatigue Difficulty concentrating Irritability Why do we sweat at night

Toxicon 56 , 855867 (2010)

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