KCNN2 (SK2) Polyclonal Antibody, 100ul Protein Expression This receptor is activated by

This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain| which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor

Gene Ontology (GO) annotations related to this gene include transferase activity

Mutations in this gene have been associated with medulloblastomas

where it may be involved in the glycosylation of alpha-dystroglycan in skeletal muscle

is a 605 amino acid protein that localizes to the mitochondrion and contains one rieske domain

KCNN2 (SK2) Polyclonal Antibody, 100ul Protein Expression This receptor is activated byAction potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by