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Description

Function of insulin-like growth factor 1 receptor in cancer resistance to chemotherapy

the underlying mechanisms are incompletely understood [16]

Pharmacokinetics of i.v

Changes in BBB transport are also evident by a decrease in cerebralspinal fluid to serum ratio of insulin [91, 99]

If a drug is taken into the gastrointestinal tract (GI tract), where it enters the hepatic portal system through the portal vein, it becomes well-metabolized and is said to show the first pass effect