Rat Heme Oxygenase 1, HO-1 ELISA Kit, 96T Gloves Transcription factor 7 encoded by

Transcription factor 7 encoded by TCF7 is a transcriptional activator that plays an important role in lymphocyte differentiation

Earlier papers referred to calreticulin as an Ro/SS-A antigen but this was later disproven

This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily

Required for homeostatic synaptic scaling of AMPA receptors

NR1H4 and VDR transactivation activity

Rat Heme Oxygenase 1, HO-1 ELISA Kit, 96T Gloves Transcription factor 7 encoded byHeme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis.